APC Anti-Mouse IL-10 Antibody[JES5-16E3]

Specifications

Catalog number

E-AB-F1197UE-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

IL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones; inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis; suppresses the delayed type hypersensitivity response; stimulates Th2 cell response (which results in elevated antibody production) ; and promotes mast cell proliferation in combination with IL-4.

Abbreviation

IL-10

Gene ID

16153

UniProt

P18893

Host

Rat

Reactivity

Mouse

Target

CSIF; Cytokine synthesis inhibitory factor; IL-10; Interleukin-10

Clonality

Monoclonal

Clone

JES5-16E3

Conjugation

APC

Applications

ICFCM

Field of Research

Immunology

Concentration

0.2 mg/mL

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Recommended Usage

6

Isotype

Rat IgG2b, κ