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Product details

APC Anti-Mouse IL-17A Antibody[TC11-18H10.1]

Catalog number E-AB-F1199E-01

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Price for E-AB-F1199E-01

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Size / count 50 Tests

Specifications

Catalog number
E-AB-F1199E-01
Size / count
50 Tests
Dry ice
No
Hazardous
No
Discontinued
No
Background
IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-κB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course.
Abbreviation
IL-17A
Gene ID
16171
UniProt
Q62386
Host
Rat
Reactivity
Mouse
Target
CTLA-8; CTLA8; Cytotoxic T-lymphocyte-associated antigen 8; IL-17; IL-17A; Interleukin-17A
Clonality
Monoclonal
Clone
TC11-18H10.1
Conjugation
APC
Applications
ICFCM
Field of Research
Cell Biology; Immunology; Neuroinflammation; Neuroscience
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation 01
https://cmjournal.biomedcentral.com/articles/10.1186/s13020-024-00904-2
Citation 02
https://onlinelibrary.wiley.com/doi/abs/10.1002/jbt.70028
Citation 03
https://www.sciencedirect.com/science/article/pii/S2095496422000681
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Rat IgG1, κ

Frequently Asked Questions

What is the catalog number for APC Anti-Mouse IL-17A Antibody[TC11-18H10.1]?

The catalog number for APC Anti-Mouse IL-17A Antibody[TC11-18H10.1] is E-AB-F1199E.

What sizes are available for APC Anti-Mouse IL-17A Antibody[TC11-18H10.1]?

APC Anti-Mouse IL-17A Antibody[TC11-18H10.1] is available in the following size(s): 50 Tests, 100 Tests, 2x 100 Tests.

How many pack sizes does APC Anti-Mouse IL-17A Antibody[TC11-18H10.1] come in?

APC Anti-Mouse IL-17A Antibody[TC11-18H10.1] is available in 3 different pack sizes.

Is APC Anti-Mouse IL-17A Antibody[TC11-18H10.1] in stock?

APC Anti-Mouse IL-17A Antibody[TC11-18H10.1] is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures APC Anti-Mouse IL-17A Antibody[TC11-18H10.1]?

APC Anti-Mouse IL-17A Antibody[TC11-18H10.1] is manufactured by Elabscience.

What is the estimated delivery time for APC Anti-Mouse IL-17A Antibody[TC11-18H10.1]?

Estimated delivery time for APC Anti-Mouse IL-17A Antibody[TC11-18H10.1] is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for APC Anti-Mouse IL-17A Antibody[TC11-18H10.1]?

The safety data sheet for APC Anti-Mouse IL-17A Antibody[TC11-18H10.1] is available here: https://789.bio/eb/58Ky18.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

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