AF/LE Purified Anti-Human CD11a Antibody[R7-1]

Specifications

Catalog number

E-AB-F12110-01

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50) .

Abbreviation

CD11a

Gene ID

3683

UniProt

P20701

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD11A protein

Target

LFA; Lymphocyte antigen; CD11A; LFA-1; LFA1A; ITGAL; LFA-1A; Ly-15; Lymphocyte antigen 15; Integrin alpha-L; CD11 antigen-like family member A; Leukocyte adhesion glycoprotein LFA-1 alpha chain (LFA-1A) ; Leukocyte function-associated molecule 1 alpha chain; integrin &alpha-L-L; LFA1

Clonality

Monoclonal

Clone

R7-1

Conjugation

None (AF/LE)

Applications

FCM

Field of Research

Signal Transduction; Immunology; Stem Cells

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Recommended Usage

6

Isotype

Mouse IgG1, κ