AF/LE Purified Anti-Human CD44 Antibody[Hermes-1]

Specifications

Catalog number

E-AB-F12150-01

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from a low or mid level of intensity to high expression levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

Abbreviation

CD44

Gene ID

960

UniProt

P16070

Host

Rat

Reactivity

Human

Target

CDw44; Epican; HUTCH-I; LHR; PGP-I

Clonality

Monoclonal

Clone

Hermes-1

Conjugation

None (AF/LE)

Applications

FCM; Block

Field of Research

Cell Biology; Immunology

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Citation 01

https://pubs.rsc.org/en/content/articlelanding/2020/bm/c9bm01394f

Citation 02

https://www.sciencedirect.com/science/article/pii/S0939641123002369

Recommended Usage

6

Isotype

Rat IgG2a, κ