PE/Cyanine7 Anti-Rat CD44H Antibody[OX-49]

Specifications

Catalog number

E-AB-F1225H-01

Size / count

50 Tests

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.

Abbreviation

CD44H

Gene ID

12505

UniProt

P26051

Host

Mouse

Reactivity

Rat

Target

CD44sH-CAM; CD44H; Pgp-1

Clonality

Monoclonal

Clone

OX-49

Conjugation

PE/Cyanine 7

Applications

FCM

Field of Research

Cell Adhesion; Cell Biology; Immunology; Stem Cells

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG2a, κ