FITC Anti-Rat CD45 Antibody[OX-1]

Specifications

Catalog number

E-AB-F1227UC-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA) . It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.

Abbreviation

CD45

Gene ID

19265

UniProt

P04157

Host

Mouse

Reactivity

Rat

Target

LCALy-5T200; Leukocyte common antigen; Ptprc; Receptor-type tyrosine-protein phosphatase C

Clonality

Monoclonal

Clone

OX-1

Conjugation

FITC

Applications

FCM

Field of Research

Cell Biology; Immunology; Inhibitory Molecules; Neuroscience; Neuroscience Cell Markers

Concentration

0.5 mg/mL

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://link.springer.com/article/10.1186/s13287-022-03018-4

Citation 02

https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8411131/

Citation 03

https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8411131/

Recommended Usage

6

Isotype

Mouse IgG1, κ