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Product details

FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7]

Catalog number E-AB-F1229C-01

Selecting a variant updates its price, size and availability.

Price for E-AB-F1229C-01

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Size / count 20 Tests

Specifications

Catalog number
E-AB-F1229C-01
Size / count
20 Tests
Dry ice
No
Hazardous
No
Discontinued
No
Background
Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
Abbreviation
CD279
Gene ID
5133
UniProt
Q15116
Host
Mouse
Reactivity
Human
Target
PD1; PDCD1; Protein PD-1; hPD-1
Clonality
Monoclonal
Clone
EH12.2H7
Conjugation
FITC
Applications
FCM
Field of Research
Cancer Biomarkers; Immunology; Inhibitory Molecules
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation 01
https://www.sciencedirect.com/science/article/pii/S1567576924010440
Citation 02
https://www.sciencedirect.com/science/article/pii/S0008874924001047
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG1, κ

Frequently Asked Questions

What is the catalog number for FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7]?

The catalog number for FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7] is E-AB-F1229C.

What sizes are available for FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7]?

FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7] is available in the following size(s): 20 Tests, 100 Tests, 2x 100 Tests.

How many pack sizes does FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7] come in?

FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7] is available in 3 different pack sizes.

Is FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7] in stock?

FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7] is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7]?

FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7] is manufactured by Elabscience.

What is the estimated delivery time for FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7]?

Estimated delivery time for FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7] is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7]?

The safety data sheet for FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7] is available here: https://789.bio/eb/LSmbLC.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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