FITC Anti-Mouse Foxp3 Antibody[3G3] — image 1 of 2

Product details

FITC Anti-Mouse Foxp3 Antibody[3G3]

Catalog number E-AB-F1238C-01

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Price for E-AB-F1238C-01

Size / count 50 Tests

Specifications

Catalog number: E-AB-F1238C-01
Size / count: 50 Tests
Dry ice: No
Hazardous: No
Discontinued: No
Background: FOXP3 is a 50-55 kD transcription factor, also known as Forkhead box protein P3, Scurfin, JM2, or IPEX. It is proposed to be a master regulatory gene and more specific marker of T regulatory cells than most cell surface markers (such as CD4 and CD25) . Transduced expression of FOXP3 in CD4+/CD25- cells has been shown to induce GITR, CD103, and CTLA4 and impart a T regulatory cell phenotype. FOXP3 is mutated in X-linked autoimmunity-allergic dysregulation syndrome (XLAAD or IPEX) in humans and in 'scurfy' mice. Overexpression of FOXP3 has been shown to lead to a hypoactive immune state suggesting that this transcriptional factor is a central regulator of T cell activity. In human, unlike in mouse, two isoforms of FOXP3 have been reported: one (FOXP3) corresponding to the canonical full-length sequence; the other (FOXP3 δ2) lacking exon 2.
Abbreviation: Foxp3
Gene ID: 50943;20371;317382
UniProt: Q99JB6
Host: Mouse
Reactivity: Mouse
Target: Forkhead box protein P3; Foxp3; IPEX; JM2
Clonality: Monoclonal
Clone: 3G3
Conjugation: FITC
Applications: ICFCM
Field of Research: Immunology
Concentration: 5 μL/Test
Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation 01: https://www.nature.com/articles/s41563-024-02054-0
Citation 02: https://pubs.acs.org/doi/abs/10.1021/acsnano.4c00392
Citation 03: https://www.sciencedirect.com/science/article/pii/S1385894724035204
Citation 04: https://www.sciencedirect.com/science/article/pii/S0142961225000158
Citation 05: https://www.sciencedirect.com/science/article/pii/S0168365925004365
Citation 06: https://www.nature.com/articles/s41419-022-05069-0
Citation 07: https://www.nature.com/articles/s41419-023-06408-5
Citation 08: https://link.springer.com/article/10.1007/s00262-024-03692-8
Citation 09: https://www.mdpi.com/1424-8247/18/1/67
Recommended Usage: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype: Mouse IgG1, κ

Frequently Asked Questions

What is the catalog number for FITC Anti-Mouse Foxp3 Antibody[3G3]?

The catalog number for FITC Anti-Mouse Foxp3 Antibody[3G3] is E-AB-F1238C.

What sizes are available for FITC Anti-Mouse Foxp3 Antibody[3G3]?

FITC Anti-Mouse Foxp3 Antibody[3G3] is available in the following size(s): 50 Tests, 100 Tests, 2x 100 Tests.

How many pack sizes does FITC Anti-Mouse Foxp3 Antibody[3G3] come in?

FITC Anti-Mouse Foxp3 Antibody[3G3] is available in 3 different pack sizes.

Is FITC Anti-Mouse Foxp3 Antibody[3G3] in stock?

FITC Anti-Mouse Foxp3 Antibody[3G3] is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures FITC Anti-Mouse Foxp3 Antibody[3G3]?

FITC Anti-Mouse Foxp3 Antibody[3G3] is manufactured by Elabscience.

What is the estimated delivery time for FITC Anti-Mouse Foxp3 Antibody[3G3]?

Estimated delivery time for FITC Anti-Mouse Foxp3 Antibody[3G3] is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for FITC Anti-Mouse Foxp3 Antibody[3G3]?

The safety data sheet for FITC Anti-Mouse Foxp3 Antibody[3G3] is available here: https://789.bio/eb/jvPqTG.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.