APC Anti-Human CD133 Antibody[W6B3C1]

Specifications

Catalog number

E-AB-F1268E-01

Size / count

20 Tests

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD133, also known as Prominin-1 and AC133 antigen, is a 120 kD pentaspan glycoprotein with 5 transmembrane domains. CD133 was initially described as a surface antigen specific for human hematopoietic stem cells and as a marker for murine neuroepithelial cells and some embryonic epithelia. Later on, CD133 was found on other stem cells, including endothelial progenitor cells, glioblastomas, neuronal, and glial stem cells. In addition to stem cells for normal tissue, CD133 was found on cancer cells, such as some leukemia cells and brain tumor cells. Although the biological function of CD133 is not completely understood, CD133 has been extensively used as a stem cell marker for normal and cancerous tissues.

Abbreviation

CD133

Gene ID

8842

UniProt

O43490

Host

Mouse

Reactivity

Human

Target

Prominin-1; AC133; Antigen AC133; CD133; CORD; CORD12; Hematopoietic stem cell antigen; MCDR; MCDR2; MSTP; MSTP061; OTTHUMP00000217744; OTTHUMP00000217745; PROM; PROM1; PROML; PROML1; Prominin-1; RP41; STGD; STGD4; hProminin

Clonality

Monoclonal

Clone

W6B3C1

Conjugation

APC

Applications

FCM

Field of Research

Cancer Biomarkers; Cell Biology; Immuno-Oncology

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://www.sciencedirect.com/science/article/pii/S2472555224000571

Citation 02

https://www.benthamdirect.com/content/journals/cmm/10.2174/0115665240268201231213095302

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG1, κ