APC Anti-Human/Mouse KLRG-1 Antibody[2F1]

Specifications

Catalog number

E-AB-F1273E-01

Size / count

20 Tests

Dry ice

No

Hazardous

No

Discontinued

No

Background

Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag) . KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer of glycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells. KLRG1 is also expressed on subsets of CD8+ and CD4+ cells, including CD4+ and CD8+ effector/memory cells, potent regulatory CD4+ T cells. KLRG1 may be involved in regulating NK cell homeostasis. KLRG6 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.

Abbreviation

KLRG-1

Gene ID

10219;50928

UniProt

Q96E93; O88713

Host

Syrian Hamster

Reactivity

Human; Mouse

Target

2F1-Ag; MAFA

Clonality

Monoclonal

Clone

2F1

Conjugation

APC

Applications

FCM

Field of Research

Immunology

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Syrian Hamster IgG