APC Anti-Mouse CD163 Antibody[S15049F]

Specifications

Catalog number

E-AB-F1295UE-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced) /155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.

Abbreviation

CD163

Gene ID

93671

UniProt

Q2VLH6

Host

Rat

Reactivity

Mouse

Target

MM130SCARI1; M130

Clonality

Monoclonal

Clone

S15049F

Conjugation

APC

Applications

FCM

Field of Research

Immunology

Concentration

0.2 mg/mL

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Recommended Usage

6

Isotype

Rat IgG2a, κ