PerCP/Cyanine5.5 Anti-Human CD163 Antibody[GHI/61]

Specifications

Catalog number

E-AB-F1298J-01

Size / count

20 Tests

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced) /155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.

Abbreviation

CD163

Gene ID

9332

UniProt

Q86VB7

Host

Mouse

Reactivity

Human

Target

ED2 (rat) Hemoglobin/Haptoglobin Complex ReceptorM130RM3/1macrophage-associated antigenp155; GHI/61

Clonality

Monoclonal

Clone

GHI/61

Conjugation

PerCP/Cyanine 5.5

Applications

FCM

Field of Research

Cell Biology; Immunology; Innate Immunity; Neuroscience; Neuroscience Cell Markers

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://www.sciencedirect.com/science/article/pii/S1567576923008287

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG1, κ