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Product details

PE Anti-Human CD49d Antibody[HP1/2]

Catalog number E-AB-F1359D-01

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Price for E-AB-F1359D-01

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Size / count 20 Tests

Specifications

Catalog number
E-AB-F1359D-01
Size / count
20 Tests
Dry ice
No
Hazardous
No
Discontinued
No
Background
CD49d is a 150 kD α integrin chain known as α4 integrin or VLA-4 α chain. It forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7) . CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. α4β7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.
Abbreviation
CD49d
Gene ID
3676
UniProt
P13612
Host
Mouse
Reactivity
Human
Target
ITGA4Integrin α4 chainα4 integrin; VLA-4 α chain
Clone
HP1/2
Conjugation
PE
Applications
FCM
Field of Research
Cell Adhesion; Cell Biology; Immunology; Innate Immunity
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG2a, κ

Frequently Asked Questions

What is the catalog number for PE Anti-Human CD49d Antibody[HP1/2]?

The catalog number for PE Anti-Human CD49d Antibody[HP1/2] is E-AB-F1359D.

What sizes are available for PE Anti-Human CD49d Antibody[HP1/2]?

PE Anti-Human CD49d Antibody[HP1/2] is available in the following size(s): 20 Tests, 100 Tests, 2x 100 Tests.

How many pack sizes does PE Anti-Human CD49d Antibody[HP1/2] come in?

PE Anti-Human CD49d Antibody[HP1/2] is available in 3 different pack sizes.

Is PE Anti-Human CD49d Antibody[HP1/2] in stock?

PE Anti-Human CD49d Antibody[HP1/2] is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PE Anti-Human CD49d Antibody[HP1/2]?

PE Anti-Human CD49d Antibody[HP1/2] is manufactured by Elabscience.

What is the estimated delivery time for PE Anti-Human CD49d Antibody[HP1/2]?

Estimated delivery time for PE Anti-Human CD49d Antibody[HP1/2] is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PE Anti-Human CD49d Antibody[HP1/2]?

The safety data sheet for PE Anti-Human CD49d Antibody[HP1/2] is available here: https://789.bio/eb/O0OePO.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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