Anti-Human CD3-FITC/CD16+CD56-PE Cocktail

Specifications

Catalog number

E-AB-FC0001-01

Size / count

20 Tests

Dry ice

No

Hazardous

No

Discontinued

No

Background

This product is a FCM antibody cocktail made up of FITC Anti-Human CD3 Antibody [Clone: OKT-3] (Mouse IgG2a, κ), PE Anti-Human CD16 Antibody [Clone: 3G8] (Mouse IgG1, κ) and PE Anti-Human CD56 Antibody [Clone: 5.1H11] (Mouse IgG1, κ) .; CD3 is a heterotetrameric protein consisting of a CD3γ, a CDδ and 2 CD3ε. It forms complex with TCR. OKT-3 recognize human CD3ε. Human CD3 is expressed on the surface of T cells and NKT cells.; CD16 is a low affinity receptor for the Fc of IgG. Human CD16 has two isoforms, CD16a and CD16b. CD16a is expressed on NK cells, activated monocytes and macrophages. CD16b is expressed on neutrophils. NK cells exert the function of ADCC by binding Fc of IgG through CD16.; CD56 is also call neural cell adhesion molecule (NCAM), expressed on neurons, glia and skeletal muscle cells. In hematopoietic cells, CD56 is also expressed on NK cells and NKT cells. CD56 can be used to detect NK cells, γ/δ T cells and activated CD8+ cells.

Reactivity

Human

Clonality

Monoclonal

Clone

OKT-3;3G8;5.1H11

Conjugation

FITC; PE

Applications

FCM

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Recommended Usage

6