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Product details

AIFM1 Polyclonal Antibody

Catalog number E-AB-10123-01

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Price for E-AB-10123-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-10123-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.
Abbreviation
AIFM1
UniProt
O95831
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human AIFM1
Target
AIFM1; AIFM1; Apoptosis inducing factor 1; mitochondrial; Apoptosis inducing factor; Apoptosis inducing factor; mitochondrion associated;1; Apoptosis-inducing factor 1; CMTX4; COWCK; COXPD6; Harlequin; Hq; mAIF; MGC111425; MGC5706; mitochondrial; Neuropathy; axonal motor-sensory; with deafness and mental retardation; neuropathy; axonal; motor-sensory with deafness and mental retardation (Cowchock syndrome) ; PDCD 8; PDCD8; Programmed cell death 8 (apoptosis inducing factor) ; Programmed cell death 8; Programmed cell death 8 isoform 1; Programmed cell death 8 isoform 2; Programmed cell death 8 isoform 3; Programmed cell death protein 8; Programmed cell death protein 8 mitochondrial; Programmed cell death protein 8 mitochondrial precursor; Programmed cell death protein 8 mitochondrial precursor; Striatal apoptosis inducing factor
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Metabolism
Purification
Affinity purification
Concentration
0.2 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
67kDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for AIFM1 Polyclonal Antibody?

The catalog number for AIFM1 Polyclonal Antibody is E-AB-10123.

What sizes are available for AIFM1 Polyclonal Antibody?

AIFM1 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does AIFM1 Polyclonal Antibody come in?

AIFM1 Polyclonal Antibody is available in 4 different pack sizes.

Is AIFM1 Polyclonal Antibody in stock?

AIFM1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures AIFM1 Polyclonal Antibody?

AIFM1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for AIFM1 Polyclonal Antibody?

Estimated delivery time for AIFM1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for AIFM1 Polyclonal Antibody?

The safety data sheet for AIFM1 Polyclonal Antibody is available here: https://789.bio/eb/nbDqHC.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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