BRCA1 Polyclonal Antibody

Catalog number E-AB-10188-01

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Price for E-AB-10188-01

Size / count 20 µL

Specifications

Catalog number: E-AB-10188-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC) . This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene.
Abbreviation: BRCA1
UniProt: P38398
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant protein of human BRCA1
Target: BRCA 1; BRCA1; BRCA1 DNA repair associated; BRCA1/BRCA2 containing complex subunit 1; BRCA1/BRCA2-containing complex; subunit 1; BRCA1; BRCAI; BRCC 1; BRCC1; Breast and ovarian cancer susceptibility protein 1; Breast Cancer 1; Breast Cancer 1 Early Onset; Breast cancer type 1 susceptibility protein; BROVCA1; FANCS; IRIS; PNCA4; PPP1R53; Protein phosphatase 1 regulatory subunit 53; PSCP; RING finger protein 53; RNF53
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Cancer; Cell Biology; Epigenetics and Nuclear Signaling
Purification: Affinity purification
Concentration: 0.3 mg/mL
Dilution: IHC 1:50-1:200
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for BRCA1 Polyclonal Antibody?

The catalog number for BRCA1 Polyclonal Antibody is E-AB-10188.

What sizes are available for BRCA1 Polyclonal Antibody?

BRCA1 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does BRCA1 Polyclonal Antibody come in?

BRCA1 Polyclonal Antibody is available in 4 different pack sizes.

Is BRCA1 Polyclonal Antibody in stock?

BRCA1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BRCA1 Polyclonal Antibody?

BRCA1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for BRCA1 Polyclonal Antibody?

Estimated delivery time for BRCA1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for BRCA1 Polyclonal Antibody?

The safety data sheet for BRCA1 Polyclonal Antibody is available here: https://789.bio/eb/ib5Ka9.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.