CRTAM Polyclonal Antibody

Specifications

Catalog number

E-AB-10260-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

The CRTAM gene is upregulated in CD4 (see MIM 186940) -positive and CD8 (see CD8A; MIM 186910) -positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.

Abbreviation

CRTAM

UniProt

O95727

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant protein of human CRTAM

Target

CD355; Class I MHC restricted T cell associated molecule; Class-I MHC-restricted T-cell-associated molecule; CRTAM; CRTAM; Cytotoxic and regulatory T cell molecule; Cytotoxic and regulatory T-cell molecule

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Immunology

Purification

Affinity purification

Concentration

0.3 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

45kDa

Observed Molecular Weight

Refer to Figures

Isotype

IgG