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Product details

FADD Polyclonal Antibody

Catalog number E-AB-10318-01

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Price for E-AB-10318-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-10318-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
Abbreviation
FADD
UniProt
Q13158
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant protein of human FADD
Target
FADD; FADD protein; FADD; Fas (TNFRSF6) associated via death domain; Fas associated via death domain; Fas associating death domain containing protein; Fas associating protein; Fas associating protein with death domain; Fas TNFRSF6 associated via death domain; FAS-associated death domain protein; FAS-associating death domain-containing protein; GIG 3; GIG3; Growth inhibiting gene 3 protein; Growth-inhibiting gene 3 protein; H sapiens mRNA for mediator of receptor induced toxicity; Mediator of receptor induced toxicity; MGC8528; MORT 1; MORT1; Protein FADD
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cell Biology
Purification
Affinity purification
Concentration
0.5 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:50-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
23kDa
Citation 01
https://www.scirp.org/journal/paperinformation.aspx?paperid=90472
Citation 02
https://www.scirp.org/journal/paperinformation.aspx?paperid=89457
Isotype
IgG

Frequently Asked Questions

What is the catalog number for FADD Polyclonal Antibody?

The catalog number for FADD Polyclonal Antibody is E-AB-10318.

What sizes are available for FADD Polyclonal Antibody?

FADD Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does FADD Polyclonal Antibody come in?

FADD Polyclonal Antibody is available in 4 different pack sizes.

Is FADD Polyclonal Antibody in stock?

FADD Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures FADD Polyclonal Antibody?

FADD Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for FADD Polyclonal Antibody?

Estimated delivery time for FADD Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for FADD Polyclonal Antibody?

The safety data sheet for FADD Polyclonal Antibody is available here: https://789.bio/eb/LizDy1.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

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