Product details

CALR Polyclonal Antibody

Catalog number E-AB-10352-01

Choose a variant (4 options)

Selecting a variant updates its price, size and availability.

Price for E-AB-10352-01

Size / count 20 µL

Specifications

Catalog number: E-AB-10352-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Calreticulin is a multifunctional protein that acts as a major Ca (2+) -binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium. The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid receptor and prevents the receptor from binding to its specific glucocorticoid response element.
Abbreviation: CALR
UniProt: P27797
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Recombinant protein of human CALR
Target: Autoantigen RO; CALR; CALR protein; CALR; Calregulin; Calreticulin; cC1qR; CRP55; CRT; CRTC; Endoplasmic reticulum resident protein 60; Epididymis secretory sperm binding protein Li 99n; ERp60; FLJ26680; grp60; HACBP; HEL S 99n; RO; Sicca syndrome antigen A (autoantigen Ro; calreticulin) ; Sicca syndrome antigen A; SSA
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Signal Transduction; Tags and Cell Markers
Purification: Affinity purification
Concentration: 0.4 mg/mL
Dilution: WB 1:1000-1:5000; IHC 1:50-1:200
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 48kDa
Citation 01: https://www.mdpi.com/2073-4409/9/12/2719
Citation 02: https://www.mdpi.com/1422-0067/19/12/3878
Isotype: IgG

Frequently Asked Questions

What is the catalog number for CALR Polyclonal Antibody?

The catalog number for CALR Polyclonal Antibody is E-AB-10352.

What sizes are available for CALR Polyclonal Antibody?

CALR Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does CALR Polyclonal Antibody come in?

CALR Polyclonal Antibody is available in 4 different pack sizes.

Is CALR Polyclonal Antibody in stock?

CALR Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CALR Polyclonal Antibody?

CALR Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for CALR Polyclonal Antibody?

Estimated delivery time for CALR Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CALR Polyclonal Antibody?

The safety data sheet for CALR Polyclonal Antibody is available here: https://789.bio/eb/OKCqTK.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.