ITGB3BP Polyclonal Antibody

Specifications

Catalog number

E-AB-10402-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.

Abbreviation

ITGB3BP

UniProt

Q13352

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant protein of human ITGB3BP

Target

Beta 3 endonexin; Beta3 endonexin; Beta3 endonexin long form; CENP R; CENPR; CENPR; Centromere protein R; endonexin; Beta-3; HSU37139; Integrin beta 3 binding protein (beta3-endonexin) ; Integrin beta 3 binding protein; NRIF 3; NRIF3; Nuclear receptor interacting factor 3; TAP 20; TAP20

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Epigenetics and Nuclear Signaling; Signal Transduction

Purification

Affinity purification

Concentration

0.7 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG