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Product details

MCM6 Polyclonal Antibody

Catalog number E-AB-10451-01

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Price for E-AB-10451-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-10451-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
Abbreviation
MCM6
UniProt
Q14566
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human MCM6
Target
DNA replication licensing factor MCM6; MCG40308; Mcm6; MCM6 minichromosome maintenance deficient 6 (MIS5 homolog; S. pombe) ; MCM6 minichromosome maintenance deficient 6; MCM6; Minichromosome maintenance complex component 6; Minichromosome maintenance deficient (mis5 S. pombe) 6; Minichromosome maintenance deficient 6 homolog; Minichromosome maintenance protein 6; Mis5; MIS5 homolog; p105MCM
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Epigenetics and Nuclear Signaling
Purification
Affinity purification
Concentration
0.6 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
93kDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for MCM6 Polyclonal Antibody?

The catalog number for MCM6 Polyclonal Antibody is E-AB-10451.

What sizes are available for MCM6 Polyclonal Antibody?

MCM6 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does MCM6 Polyclonal Antibody come in?

MCM6 Polyclonal Antibody is available in 4 different pack sizes.

Is MCM6 Polyclonal Antibody in stock?

MCM6 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MCM6 Polyclonal Antibody?

MCM6 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for MCM6 Polyclonal Antibody?

Estimated delivery time for MCM6 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MCM6 Polyclonal Antibody?

The safety data sheet for MCM6 Polyclonal Antibody is available here: https://789.bio/eb/5Oazj1.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

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