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Product details

PTCH1 Polyclonal Antibody

Catalog number E-AB-10571-01

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Price for E-AB-10571-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-10571-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.
Abbreviation
PTCH1
UniProt
Q13635
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant protein of human PTCH1
Target
PTC; BCNS; HPE7; PTC1; PTCH; NBCCS; PTCH11
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cell Biology; Neuroscience; Stem Cells
Purification
Affinity purification
Concentration
0.5 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
161kDa
Citation 01
https://www.sciencedirect.com/science/article/pii/S2352396419307820
Isotype
IgG

Frequently Asked Questions

What is the catalog number for PTCH1 Polyclonal Antibody?

The catalog number for PTCH1 Polyclonal Antibody is E-AB-10571.

What sizes are available for PTCH1 Polyclonal Antibody?

PTCH1 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does PTCH1 Polyclonal Antibody come in?

PTCH1 Polyclonal Antibody is available in 4 different pack sizes.

Is PTCH1 Polyclonal Antibody in stock?

PTCH1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PTCH1 Polyclonal Antibody?

PTCH1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for PTCH1 Polyclonal Antibody?

Estimated delivery time for PTCH1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PTCH1 Polyclonal Antibody?

The safety data sheet for PTCH1 Polyclonal Antibody is available here: https://789.bio/eb/Kq1SuT.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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