PVHL Polyclonal Antibody

Catalog number E-AB-10671-01

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Price for E-AB-10671-01

Size / count 20 µL

Specifications

Catalog number: E-AB-10671-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Abbreviation: VHL
UniProt: P40337
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant protein of human VHL
Target: Elongin binding protein; G7 protein; HRCA 1; HRCA1; Protein G7; pVHL; RCA 1; RCA1; VHL 1; VHL; VHL; VHL1; VHLH; Von Hippel Lindau disease tumor suppressor; von Hippel Lindau syndrome; von Hippel Lindau tumor suppressor; Von Hippel Lindau tumor suppressor; E3 ubiquitin protein ligase; Von Hippel-Lindau disease tumor suppressor
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Metabolism
Purification: Affinity purification
Concentration: 0.4 mg/mL
Dilution: IHC 1:50-1:200
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for PVHL Polyclonal Antibody?

The catalog number for PVHL Polyclonal Antibody is E-AB-10671.

What sizes are available for PVHL Polyclonal Antibody?

PVHL Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does PVHL Polyclonal Antibody come in?

PVHL Polyclonal Antibody is available in 4 different pack sizes.

Is PVHL Polyclonal Antibody in stock?

PVHL Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PVHL Polyclonal Antibody?

PVHL Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for PVHL Polyclonal Antibody?

Estimated delivery time for PVHL Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PVHL Polyclonal Antibody?

The safety data sheet for PVHL Polyclonal Antibody is available here: https://789.bio/eb/CyrLeD.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.