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Product details

XBP1 Polyclonal Antibody

Catalog number E-AB-10674-01

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Price for E-AB-10674-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-10674-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1) . The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1 (S), which is the functionally active transcription factor.
Abbreviation
XBP1
UniProt
P17861
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein of human XBP1
Target
Tax responsive element binding protein 5; Tax-responsive element-binding protein 5; TREB5; X box binding protein 1; X box binding protein 2; X-box-binding protein 1; XBP 1; XBP-1; XBP1; XBP1; XBP2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Epigenetics and Nuclear Signaling
Purification
Affinity purification
Concentration
0.2 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

Frequently Asked Questions

What is the catalog number for XBP1 Polyclonal Antibody?

The catalog number for XBP1 Polyclonal Antibody is E-AB-10674.

What sizes are available for XBP1 Polyclonal Antibody?

XBP1 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does XBP1 Polyclonal Antibody come in?

XBP1 Polyclonal Antibody is available in 4 different pack sizes.

Is XBP1 Polyclonal Antibody in stock?

XBP1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures XBP1 Polyclonal Antibody?

XBP1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for XBP1 Polyclonal Antibody?

Estimated delivery time for XBP1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for XBP1 Polyclonal Antibody?

The safety data sheet for XBP1 Polyclonal Antibody is available here: https://789.bio/eb/Ly9O4S.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

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