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Product details

FLT3 Polyclonal Antibody

Catalog number E-AB-10844-01

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Price for E-AB-10844-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-10844-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
Abbreviation
FLT3
UniProt
P36888
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant protein of human FLT3
Target
CD 135; CD135; CD135 antigen; Fetal liver kinase 2; FL cytokine receptor; Flk 2; Flk2; Flt 3; FLT-3; Flt3; FLT3; FMS like tyrosine kinase 3; Fms related tyrosine kinase 3; Fms-like tyrosine kinase 3; Growth factor receptor tyrosine kinase type III; Ly-72; OTTHUMP0000004234; Receptor type tyrosine protein kinase FLT3; Stem cell tyrosine kinase 1; Stk 1; STK-1; Stk1; Tyrosine protein kinase receptor FLT3; Tyrosine-protein kinase receptor FLT3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Immunology; Signal Transduction
Purification
Affinity purification
Concentration
0.5 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

Frequently Asked Questions

What is the catalog number for FLT3 Polyclonal Antibody?

The catalog number for FLT3 Polyclonal Antibody is E-AB-10844.

What sizes are available for FLT3 Polyclonal Antibody?

FLT3 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does FLT3 Polyclonal Antibody come in?

FLT3 Polyclonal Antibody is available in 4 different pack sizes.

Is FLT3 Polyclonal Antibody in stock?

FLT3 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures FLT3 Polyclonal Antibody?

FLT3 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for FLT3 Polyclonal Antibody?

Estimated delivery time for FLT3 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for FLT3 Polyclonal Antibody?

The safety data sheet for FLT3 Polyclonal Antibody is available here: https://789.bio/eb/frz5aH.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

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