THOC7 Polyclonal Antibody

Specifications

Catalog number

E-AB-10940-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

NIF3L1 BP1 (Ngg1-interacting factor 3-like 1 binding protein 1), also known as THOC7 (THO complex subunit 7 homolog), fSAP24 or hTREX30, is a 204 amino acid cytoplasmic and nuclear protein that belongs to the THOC7 family and interacts with NIF3L1. NIF3L1 BP1 is a component of the THO/TREX complex that is recruited to transcribed genes and travels along with RNA polymerase II (Pol II) during elongation, coupling Pol II with RNA splicing and export factors. The THO/TREX complex also plays a role in the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The gene that encodes NIF3L1 BP1 maps to human chromosome 3p14.1.

Abbreviation

THOC7

UniProt

Q6I9Y2

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Recombinant protein of human THOC7

Target

FLJ23445; fSAP24; Functional spliceosome associated protein 24; Functional spliceosome-associated protein 24; hTREX30; Ngg1 interacting factor 3 like 1 binding protein 1; Ngg1 interacting factor 3 like protein 1 binding protein 1; Ngg1-interacting factor 3-like protein 1-binding protein 1; NIF3L1 binding protein 1; NIF3L1-binding protein 1; NIF3L1BP1; THO complex 7 homolog (Drosophila) ; THO complex 7 homolog; THO complex subunit 7 homolog; THOC 7; thoc7; THOC7

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Epigenetics and Nuclear Signaling

Purification

Affinity purification

Concentration

0.3 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:25-1:100

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

24kDa

Isotype

IgG