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Product details

CYP2E1 Polyclonal Antibody

Catalog number E-AB-11118-01

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Price for E-AB-11118-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-11118-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
Abbreviation
CYP2E1
UniProt
P05181
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human CYP2E1
Target
4-nitrophenol 2-hydroxylase; CP2E1; CPE1; CYP2E; Cyp2e1; CYPIIE1; Cytochrome P450 2E1; Cytochrome P450 isozyme 3A; Cytochrome P450 LM3A; Cytochrome P450; family 2; subfamily e; polypeptide 1; cytochrome P450; subfamily IIE (ethanol-inducible) ; polypeptide 1; Cytochrome P450; subfamily IIE; Cytochrome P450-ALC; Cytochrome P450-J; Cytochrome P450RLM6; EC 1.14.13.-; EC 1.14.13.n7; Ethanol-inducible P450; Flavoprotein-linked monooxygenase; MGC133529; Microsomal monooxygenase; OTTHUMP00000020813; OTTHUMP00000046571; P450 ALC; P450-J; P450C2E; P450J; P450RLM6; Xenobiotic monooxygenase
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cardiovascular; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
0.5 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
57kDa
Citation 01
https://onlinelibrary.wiley.com/doi/abs/10.1111/jfbc.13836
Isotype
IgG

Frequently Asked Questions

What is the catalog number for CYP2E1 Polyclonal Antibody?

The catalog number for CYP2E1 Polyclonal Antibody is E-AB-11118.

What sizes are available for CYP2E1 Polyclonal Antibody?

CYP2E1 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does CYP2E1 Polyclonal Antibody come in?

CYP2E1 Polyclonal Antibody is available in 4 different pack sizes.

Is CYP2E1 Polyclonal Antibody in stock?

CYP2E1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CYP2E1 Polyclonal Antibody?

CYP2E1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for CYP2E1 Polyclonal Antibody?

Estimated delivery time for CYP2E1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CYP2E1 Polyclonal Antibody?

The safety data sheet for CYP2E1 Polyclonal Antibody is available here: https://789.bio/eb/S08iXD.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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