TBXAS1 Polyclonal Antibody

Specifications

Catalog number

E-AB-11128-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Abbreviation

TBXAS1

UniProt

P24557

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant protein of human TBXAS1

Target

BDPLT14; CYP5; CYP5A1; Cytochrome P450 5A1; Cytochrome P450; family 5; subfamily A; polypeptide 1; FLJ52771; GHOSAL; Platelet cytochrome P450 subfamily V; Tbxas1; THAS; THAS; Thromboxane A synthase 1 (platelet) ; Thromboxane A synthase 1 (platelet; cytochrome P450; family 5; subfamily A) ; Thromboxane A synthase 1; Thromboxane A synthase 1 platelet cytochrome P450 subfamily V; Thromboxane-A synthase; TS; TXA synthase; TXAS; TXS

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Cell Biology; Cardiovascular; Metabolism; Signal Transduction

Purification

Affinity purification

Concentration

0.7 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG