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Product details

DRG1 Polyclonal Antibody

Catalog number E-AB-11166-01

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Price for E-AB-11166-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-11166-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
DRG1 (developmentally regulated GTP binding protein 1), also known as NEDD3 (neural precursor cell expressed developmentally down-regulated protein 3), is a 367 amino acid protein that localizes to the cytoplasm and belongs to the GTP1/OBG family. Expressed at high levels in heart, kidney and skeletal muscle and at lower levels in brain, liver, placenta, lung, colon and spleen, DRG1 binds to TAL1 and TAL2 and is thought to play a role in cell proliferation and differentiation, as well as in apoptosis, suggesting a role in tumor formation and metastasis. DRG1 is subject to polyubiquitination and sumoylation, the former of which induces proteolytic degradation. The gene encoding DRG1 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
Abbreviation
DRG1
UniProt
Q9Y295
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant protein of human DRG1
Target
Developmentally regulated GTP binding protein 1; Developmentally-regulated GTP-binding protein 1; DKFZp434N1827; DRG 1; DRG-1; DRG1; DRG1; NEDD 3; NEDD-3; NEDD3; Neural precursor cell expressed developmentally down regulated protein 3; Neural precursor cell expressed developmentally down-regulated protein 3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cell Biology; Signal Transduction
Purification
Affinity purification
Concentration
0.5 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
41kDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for DRG1 Polyclonal Antibody?

The catalog number for DRG1 Polyclonal Antibody is E-AB-11166.

What sizes are available for DRG1 Polyclonal Antibody?

DRG1 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does DRG1 Polyclonal Antibody come in?

DRG1 Polyclonal Antibody is available in 4 different pack sizes.

Is DRG1 Polyclonal Antibody in stock?

DRG1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures DRG1 Polyclonal Antibody?

DRG1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for DRG1 Polyclonal Antibody?

Estimated delivery time for DRG1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for DRG1 Polyclonal Antibody?

The safety data sheet for DRG1 Polyclonal Antibody is available here: https://789.bio/eb/j1u5iD.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

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