HSD17B12 Polyclonal Antibody

Specifications

Catalog number

E-AB-11302-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women.

Abbreviation

HSD17B12

UniProt

Q53GQ0

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant protein of human HSD17B12

Target

12;3-ketoacyl-CoA reductase; short chain;17 beta HSD 12;17 beta hydroxysteroid dehydrogenase 12;17-@beta-HSD XII;17-@beta-hydroxysteroid dehydrogenase XII;17-beta-HSD 12;17-beta-hydroxysteroid dehydrogenase 12;17beta HSD type 12;3 ketoacyl CoA reductase;3-ketoacyl-CoA reductase; DHB12; Estradiol 17 beta dehydrogenase 12; Estradiol 17-beta-dehydrogenase 12; HSD17B12; Hydroxysteroid (17-beta) dehydrogenase 12; KAR; KIK-I; Kik1; SDR12C1; Short chain dehydrogenase/reductase family 12C member 1; Steroid dehydrogenase homolog

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cell Biology; Metabolism; Signal Transduction

Purification

Affinity purification

Concentration

0.4 mg/mL

Dilution

WB 1:200-1:1000; IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

34kDa

Isotype

IgG