MRE11 Polyclonal Antibody — image 1 of 2

Product details

MRE11 Polyclonal Antibody

Catalog number E-AB-11403-01

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Price for E-AB-11403-01

Size / count 20 µL

Specifications

Catalog number: E-AB-11403-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Abbreviation: MRE11A
UniProt: P49959
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Recombinant protein of human MRE11A
Target: AT like disease; Ataxia telangiectasia disorder like; ATLD; DNA recombination and repair protein; Double strand break repair protein MRE11A; Double-strand break repair protein MRE11A; endo/exonuclease Mre11; HNGS1; meiotic recombination (S. cerevisiae) 11 homolog A; Meiotic recombination 11 homolog 1; meiotic recombination 11 homolog A (S. cerevisiae) ; Meiotic recombination 11 homolog A; MmMRE11A; Mre 11; MRE 11a; MRE 11b; MRE11 homolog 1; MRE11 homolog A; MRE11 homolog double strand break repair nuclease; MRE11 meiotic recombination 11 homolog A (S. cerevisiae) ; MRE11 meiotic recombination 11 homolog A; MRE11; MRE11A; MRE11b; OTTHUMP00000236830; OTTHUMP00000236831; OTTHUMP00000236832; OTTHUMP00000236833
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Epigenetics and Nuclear Signaling
Purification: Affinity purification
Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:100-1:300
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 81kDa
Citation 01: https://www.nature.com/articles/s41467-021-26293-w
Citation 02: https://www.tandfonline.com/doi/abs/10.1080/15384047.2021.2020060
Isotype: IgG

Frequently Asked Questions

What is the catalog number for MRE11 Polyclonal Antibody?

The catalog number for MRE11 Polyclonal Antibody is E-AB-11403.

What sizes are available for MRE11 Polyclonal Antibody?

MRE11 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does MRE11 Polyclonal Antibody come in?

MRE11 Polyclonal Antibody is available in 4 different pack sizes.

Is MRE11 Polyclonal Antibody in stock?

MRE11 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MRE11 Polyclonal Antibody?

MRE11 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for MRE11 Polyclonal Antibody?

Estimated delivery time for MRE11 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MRE11 Polyclonal Antibody?

The safety data sheet for MRE11 Polyclonal Antibody is available here: https://789.bio/eb/KqjfT4.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.