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Product details

E2F4 Polyclonal Antibody

Catalog number E-AB-12375-01

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Price for E-AB-12375-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-12375-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two.
Abbreviation
E2F4
UniProt
Q16254
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human E2F4
Target
E2F 4; E2F transcription factor 4; E2F transcription factor 4 p107/p130 binding; E2F-4; E2F4; E2F4; p107/p130 binding protein; Transcription factor E2F 4; Transcription factor E2F4
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Stem Cells
Purification
Affinity purification
Concentration
0.5 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

Frequently Asked Questions

What is the catalog number for E2F4 Polyclonal Antibody?

The catalog number for E2F4 Polyclonal Antibody is E-AB-12375.

What sizes are available for E2F4 Polyclonal Antibody?

E2F4 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does E2F4 Polyclonal Antibody come in?

E2F4 Polyclonal Antibody is available in 4 different pack sizes.

Is E2F4 Polyclonal Antibody in stock?

E2F4 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures E2F4 Polyclonal Antibody?

E2F4 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for E2F4 Polyclonal Antibody?

Estimated delivery time for E2F4 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for E2F4 Polyclonal Antibody?

The safety data sheet for E2F4 Polyclonal Antibody is available here: https://789.bio/eb/fH8unT.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

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