FOXB1 Polyclonal Antibody

Specifications

Catalog number

E-AB-12418-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.

Abbreviation

FOXB1

UniProt

Q99853

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human FOXB1

Target

FKH 5; FKH5; Forkhead box B1; Forkhead box protein B1; FOX B1; FOXB 1; HFKH 5; HFKH-5; HFKH5; Transcription factor FKH 5; Transcription factor FKH5

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Epigenetics and Nuclear Signaling

Purification

Affinity purification

Concentration

0.2 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG