MAP2K2 Polyclonal Antibody — image 1 of 2

Product details

MAP2K2 Polyclonal Antibody

Catalog number E-AB-12553-01

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Price for E-AB-12553-01

Size / count 20 µL

Specifications

Catalog number: E-AB-12553-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.
Abbreviation: MAP2K2
UniProt: P36507
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Synthetic peptide of human MAP2K2
Target: Cardiofaciocutaneous syndrome; CFC syndrome; CFC4; Dual specificity mitogen activated protein kinase kinase 2; Dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 2; FLJ26075; MAP kinase kinase 2; map2k2; MAPK / ERK kinase 2; MAPK/ERK kinase 2; MAPKK 2; MAPKK2; MEK 2; MEK2; Microtubule associated protein kinase kinase 2; Mitogen activated protein kinase kinase 2; Mitogen activated protein kinase kinase 2 p45; MKK 2; MKK2; MP2K2; OTTHUMP00000165826; OTTHUMP00000165827; PRKMK 2; PRKMK2
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Signal Transduction
Purification: Affinity purification
Concentration: 1 mg/mL
Dilution: WB 1:1000-1:5000; IHC 1:100-1:300
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 44kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for MAP2K2 Polyclonal Antibody?

The catalog number for MAP2K2 Polyclonal Antibody is E-AB-12553.

What sizes are available for MAP2K2 Polyclonal Antibody?

MAP2K2 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does MAP2K2 Polyclonal Antibody come in?

MAP2K2 Polyclonal Antibody is available in 4 different pack sizes.

Is MAP2K2 Polyclonal Antibody in stock?

MAP2K2 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MAP2K2 Polyclonal Antibody?

MAP2K2 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for MAP2K2 Polyclonal Antibody?

Estimated delivery time for MAP2K2 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MAP2K2 Polyclonal Antibody?

The safety data sheet for MAP2K2 Polyclonal Antibody is available here: https://789.bio/eb/CWfnLO.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.