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Product details

CHRNA7 Polyclonal Antibody

Catalog number E-AB-12583-01

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Price for E-AB-12583-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-12583-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A) . Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.
Abbreviation
CHRFAM7A
UniProt
P36544
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human CHRFAM7A
Target
7nAChR; a7 nicotinic acetylcholine receptor; acetylcholine receptor; neuronal nicotinic; alpha-7 subunit; ACHA7; AChR; Acra7; alpha 7 neuronal nicotinic acetylcholine receptor; alpha-7 nicotinic cholinergic receptor subunit; alpha7; cholinergic receptor; neuronal nicotinic; alpha polypeptide 7; cholinergic receptor; nicotinic; alpha 7 (neuronal) ; cholinergic receptor; nicotinic; alpha 7; cholinergic receptor; nicotinic; alpha polypeptide 7; CHRNA7; CHRNA7-2; NACHRA7; neuronal acetylcholine receptor protein; alpha-7 chain; Neuronal acetylcholine receptor subunit alpha-7
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Metabolism; Neuroscience
Purification
Affinity purification
Concentration
0.3 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
46kDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for CHRNA7 Polyclonal Antibody?

The catalog number for CHRNA7 Polyclonal Antibody is E-AB-12583.

What sizes are available for CHRNA7 Polyclonal Antibody?

CHRNA7 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does CHRNA7 Polyclonal Antibody come in?

CHRNA7 Polyclonal Antibody is available in 4 different pack sizes.

Is CHRNA7 Polyclonal Antibody in stock?

CHRNA7 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CHRNA7 Polyclonal Antibody?

CHRNA7 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for CHRNA7 Polyclonal Antibody?

Estimated delivery time for CHRNA7 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CHRNA7 Polyclonal Antibody?

The safety data sheet for CHRNA7 Polyclonal Antibody is available here: https://789.bio/eb/GOO000.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

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