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Product details

RBFOX3 Polyclonal Antibody

Catalog number E-AB-12595-01

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Price for E-AB-12595-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-12595-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Immunoprecipitation and mass spectrometry of the two major NeuN species at 45–50 kDa identified both as the RNA binding protein Rbfox3 (a member of the Fox family of alternative splicing factors), confirming and extending the identification of the 45 kDa band as Rbfox3. Mapping of the anti-NeuN reactive epitopes in both R3hdm2 and Rbfox3 reveals a common proline- and glutamine-rich domain that lies at the N-terminus of the Rbfox3 protein. Nuclear Rbfox3 isoforms can also enhance the inclusion of cryptic exons in the Rbfox2 mRNA, resulting in nonsense-mediated decay of the message, thereby contributing to the negative regulation of Rbfox2 by Rbfox3 through a novel mechanism.
Abbreviation
RBFOX3
UniProt
A6NFN3
Host
Rabbit
Reactivity
Human ; Mouse
Immunogen
Synthetic peptide of human RBFOX3
Target
FLJ56884; FLJ58356; Fox-1 homolog C; fox1 homolog C; Fox3; FOX3NeuN; hexaribonucleotide binding protein 3; HRNBP3; NEUN; neuronal nuclei; Rbfox3; RFOX3; RNA binding protein fox-1 homolog 3; RNA binding protein; fox 1 homolog (C. elegans) 3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Neuroscience; Tags and Cell Markers
Purification
Affinity purification
Concentration
0.1 mg/mL
Dilution
WB 1:200-1:1000; IHC 1:50-200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
34kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

Frequently Asked Questions

What is the catalog number for RBFOX3 Polyclonal Antibody?

The catalog number for RBFOX3 Polyclonal Antibody is E-AB-12595.

What sizes are available for RBFOX3 Polyclonal Antibody?

RBFOX3 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does RBFOX3 Polyclonal Antibody come in?

RBFOX3 Polyclonal Antibody is available in 4 different pack sizes.

Is RBFOX3 Polyclonal Antibody in stock?

RBFOX3 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures RBFOX3 Polyclonal Antibody?

RBFOX3 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for RBFOX3 Polyclonal Antibody?

Estimated delivery time for RBFOX3 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for RBFOX3 Polyclonal Antibody?

The safety data sheet for RBFOX3 Polyclonal Antibody is available here: https://789.bio/eb/yfz5yH.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

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