ACO1 Polyclonal Antibody

Catalog number E-AB-12938-01

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Price for E-AB-12938-01

Size / count 20 µL

Specifications

Catalog number: E-AB-12938-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs) . IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.
Abbreviation: ACO1
UniProt: P21399
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Synthetic peptide of human ACO1
Target: ACO 1; ACO1; ACOC; Aconitase 1 soluble; Aconitase; Aconitase1; Aconitate hydratase; ACONS; Citrate hydro lyase; Citrate hydro-lyase; Cytoplasmic aconitate hydratase; Ferritin repressor protein; IRE BP 1; IRE-BP 1; IREB 1; IREB1; IREBP; IREBP1; Iron regulatory protein 1; Iron responsive element binding protein 1; Iron-responsive element-binding protein 1; IRP 1; IRP1; OTTHUMP00000045233
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism; Signal Transduction
Purification: Affinity purification
Concentration: 0.4 mg/mL
Dilution: IHC 1:50-1:200
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for ACO1 Polyclonal Antibody?

The catalog number for ACO1 Polyclonal Antibody is E-AB-12938.

What sizes are available for ACO1 Polyclonal Antibody?

ACO1 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does ACO1 Polyclonal Antibody come in?

ACO1 Polyclonal Antibody is available in 4 different pack sizes.

Is ACO1 Polyclonal Antibody in stock?

ACO1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ACO1 Polyclonal Antibody?

ACO1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for ACO1 Polyclonal Antibody?

Estimated delivery time for ACO1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ACO1 Polyclonal Antibody?

The safety data sheet for ACO1 Polyclonal Antibody is available here: https://789.bio/eb/f1inb1.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.