PIAS2 Polyclonal Antibody

Specifications

Catalog number

E-AB-13005-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1.

Abbreviation

PIAS2

UniProt

O75928

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human PIAS2

Target

Androgen receptor interacting protein 3; Androgen receptor-interacting protein 3; ARIP3; DAB2 interacting protein; DAB2-interacting protein; DIP; E3 SUMO protein ligase PIAS2; E3 SUMO-protein ligase PIAS2; MIZ; Miz1; Msx interacting zinc finger protein; Msx-interacting zinc finger protein; PIAS NY protein; PIAS-NY protein; PIAS2; PIAS2; PIASX; PIASX-ALPHA; PIASX-BETA; Protein inhibitor of activated STAT x; Protein inhibitor of activated STAT;2; Protein inhibitor of activated STAT2; SIZ2; Zinc finger; MIZ-type containing 4; ZMIZ4

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cell Biology; Epigenetics and Nuclear Signaling

Purification

Affinity purification

Concentration

0.6 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG