CYP2D6 Polyclonal Antibody

Catalog number E-AB-13178-01

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Price for E-AB-13178-01

Size / count 20 µL

Specifications

Catalog number: E-AB-13178-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug; sparteine and propafenone, both anti-arrythmic drugs; and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Abbreviation: CYP2D6
UniProt: P10635
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide of human CYP2D6
Target: CPD6; CYP2D; CYP2D6; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; CYP2DL1; CYPIID6; Cytochrome P450 DB1; Cytochrome P450 family 2 subfamily D member 6; Cytochrome P450 family 2 subfamily D polypeptide 6; Debrisoquine 4 hydroxylase; Flavoprotein linked monooxygenase; Microsomal monooxygenase; P450 DB1; P450C2D; P450DB1; Xenobiotic monooxygenase
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Cardiovascular; Metabolism; Signal Transduction
Purification: Affinity purification
Concentration: 0.2 mg/mL
Dilution: IHC 1:50-1:200
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for CYP2D6 Polyclonal Antibody?

The catalog number for CYP2D6 Polyclonal Antibody is E-AB-13178.

What sizes are available for CYP2D6 Polyclonal Antibody?

CYP2D6 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does CYP2D6 Polyclonal Antibody come in?

CYP2D6 Polyclonal Antibody is available in 4 different pack sizes.

Is CYP2D6 Polyclonal Antibody in stock?

CYP2D6 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CYP2D6 Polyclonal Antibody?

CYP2D6 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for CYP2D6 Polyclonal Antibody?

Estimated delivery time for CYP2D6 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CYP2D6 Polyclonal Antibody?

The safety data sheet for CYP2D6 Polyclonal Antibody is available here: https://789.bio/eb/HyfnH0.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.