AIMP1 Polyclonal Antibody

Specifications

Catalog number

E-AB-13210-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.

Abbreviation

AIMP1

UniProt

Q12904

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human AIMP1

Target

AIMP 1; Aimp1; AIMP1/p43; AIMP1; Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1; ARS interacting multifunctional protein 1; EMAP 2; EMAP-2; EMAP-II; EMAP2; EMAPII; Endothelial monocyte activating polypeptide 2; Endothelial monocyte activating polypeptide; Endothelial monocyte-activating polypeptide 2; Endothelial monocyte-activating polypeptide II; HLD3; Multisynthase complex auxiliary component p43; Multisynthetase complex auxiliary component p43; OTTHUMP00000219673; p43; Scye 1; Scye1; Scye1; formerly; Small inducible cytokine subfamily E member 1; Small inducible cytokine subfamily E; member 1 (endothelial monocyte-activating) ; Small inducible cytokine subfamily E; member 1; formerly

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Cell Biology; Cardiovascular; Epigenetics and Nuclear Signaling; Immunology; Tags and Cell Markers

Purification

Affinity purification

Concentration

1.1 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

34kDa

Isotype

IgG