HMGCS1 Polyclonal Antibody

Catalog number E-AB-13295-01

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Price for E-AB-13295-01

Size / count 20 µL

Specifications

Catalog number: E-AB-13295-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: HMG-CoA Synthase exists as both a mitochondrial (mHMGCS) and cytoplasmic (cHMGCS) enzyme that condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA. The HMG-CoA produced by cHMGCS is transformed into mevalonate by HMG-CoA reductase, which starts isoprenoid biosynthesis. End products of the isoprenoid pathway include cholesterol, ubiquinone, dolichol, isopentenyl adenosine and farnesyl groups. mHMGCS, together with HMG-CoA Lyase, is responsible for ketone body biosynthesis. mHMGCS is expressed in liver and kidney. Fasting, cAMP and fatty acids increase the level of transcription of mHMGCS, while feeding and insulin repress it. A regulatory element within the mHMGCS promoter confers transcriptional regulation by PPAR, RXR, COUP-TF and HNF-4.
Abbreviation: HMGCS1
UniProt: Q01581
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide of human HMGCS1
Target: 3 hydroxy 3 methylglutaryl Coenzyme A synthase 1 (soluble) ;3-hydroxy-3-methylglutaryl coenzyme A synthase; cytoplasmic; EC 2.3.3.10; HMCS1; HMG CoA synthase; HMG-CoA synthase; HMGCS; HMGCS1; Hydroxymethylglutaryl CoA synthase; cytoplasmic; Hydroxymethylglutaryl-CoA synthase; MGC90332
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Cardiovascular; Metabolism; Signal Transduction
Purification: Affinity purification
Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:50-1:200
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 57kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for HMGCS1 Polyclonal Antibody?

The catalog number for HMGCS1 Polyclonal Antibody is E-AB-13295.

What sizes are available for HMGCS1 Polyclonal Antibody?

HMGCS1 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does HMGCS1 Polyclonal Antibody come in?

HMGCS1 Polyclonal Antibody is available in 4 different pack sizes.

Is HMGCS1 Polyclonal Antibody in stock?

HMGCS1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HMGCS1 Polyclonal Antibody?

HMGCS1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for HMGCS1 Polyclonal Antibody?

Estimated delivery time for HMGCS1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HMGCS1 Polyclonal Antibody?

The safety data sheet for HMGCS1 Polyclonal Antibody is available here: https://789.bio/eb/4m9yH0.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.