HSD11B2 Polyclonal Antibody

Catalog number E-AB-13311-01

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Price for E-AB-13311-01

Size / count 20 µL

Specifications

Catalog number: E-AB-13311-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor.
Abbreviation: HSD11B2
UniProt: P80365
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide of human HSD11B2
Target: 11 beta HSD2;11 beta hydroxysteroid dehydrogenase type 2;11 DH2;11-beta-HSD2;11-beta-hydroxysteroid dehydrogenase type 2;11-DH2; AME; AME1; Corticosteroid 11 beta dehydrogenase isozyme 2; Corticosteroid 11-beta-dehydrogenase isozyme 2; DHI2; HSD11B2; HSD11K; HSD2; Hydroxysteroid 11 beta dehydrogenase 2; Hydroxysteroid 11 beta dehydrogenase isoenzyme 2; NAD dependent 11 beta hydroxysteroid dehydrogenase; NAD-dependent 11-beta-hydroxysteroid dehydrogenase; SDR9C3; Short chain dehydrogenase/reductase family 9C; member 3
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Cancer; Cell Biology; Cardiovascular; Metabolism; Signal Transduction
Purification: Affinity purification
Concentration: 0.6 mg/mL
Dilution: IHC 1:50-1:200
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for HSD11B2 Polyclonal Antibody?

The catalog number for HSD11B2 Polyclonal Antibody is E-AB-13311.

What sizes are available for HSD11B2 Polyclonal Antibody?

HSD11B2 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does HSD11B2 Polyclonal Antibody come in?

HSD11B2 Polyclonal Antibody is available in 4 different pack sizes.

Is HSD11B2 Polyclonal Antibody in stock?

HSD11B2 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HSD11B2 Polyclonal Antibody?

HSD11B2 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for HSD11B2 Polyclonal Antibody?

Estimated delivery time for HSD11B2 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HSD11B2 Polyclonal Antibody?

The safety data sheet for HSD11B2 Polyclonal Antibody is available here: https://789.bio/eb/S0mbv9.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.