CASP3 Polyclonal Antibody — image 1 of 2

Product details

CASP3 Polyclonal Antibody

Catalog number E-AB-13815-01

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Price for E-AB-13815-01

Size / count 20 µL

Specifications

Catalog number: E-AB-13815-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
Abbreviation: CASP3
UniProt: P42574
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Recombinant protein of human CASP3
Target: A830040C14Rik; Apopain; CASP-3; CASP3; CASP3; Casp3a; Caspase 3; Caspase 3; apoptosis-related cysteine peptidase; Caspase 3; apoptosis-related cysteine protease; Caspase 3; apoptosis-related cysteine protease a; Caspase-3 subunit p12; CC3; CPP-32; CPP32; CPP32B; Cysteine protease CPP32; EC 3.4.22.56; LICE; mldy; OTTHUMP00000165052; OTTHUMP00000165053; OTTHUMP00000165054; PARP cleavage protease; Procaspase3; Protein Yama; SCA 1; SCA-1; SREBP cleavage activity 1; Yama
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Cell Biology; Metabolism; Neuroscience
Purification: Affinity purification
Concentration: 0.5 mg/mL
Dilution: WB 1:200-1:1000; IHC 1:50-1:200
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 32kDa
Citation 01: https://www.sciencedirect.com/science/article/pii/S1382668922001739
Citation 02: https://eurjmedres.biomedcentral.com/articles/10.1186/s40001-022-00747-3
Citation 03: https://europepmc.org/article/pmc/pmc8333701?javascript_support=no
Citation 04: https://www.sciencedirect.com/science/article/pii/S0300483X18303937
Citation 05: https://link.springer.com/article/10.1007/s12011-018-1535-3
Citation 06: https://www.sciencedirect.com/science/article/pii/S2666027X22000093
Isotype: IgG

Frequently Asked Questions

What is the catalog number for CASP3 Polyclonal Antibody?

The catalog number for CASP3 Polyclonal Antibody is E-AB-13815.

What sizes are available for CASP3 Polyclonal Antibody?

CASP3 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does CASP3 Polyclonal Antibody come in?

CASP3 Polyclonal Antibody is available in 4 different pack sizes.

Is CASP3 Polyclonal Antibody in stock?

CASP3 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CASP3 Polyclonal Antibody?

CASP3 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for CASP3 Polyclonal Antibody?

Estimated delivery time for CASP3 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CASP3 Polyclonal Antibody?

The safety data sheet for CASP3 Polyclonal Antibody is available here: https://789.bio/eb/m10uXH.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.