XBP1 Polyclonal Antibody

Catalog number E-AB-14437-01

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Price for E-AB-14437-01

Size / count 20 µL

Specifications

Catalog number: E-AB-14437-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1) . The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1 (S), which is the functionally active transcription factor.
Abbreviation: XBP1
UniProt: P17861
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant protein of human XBP1
Target: Tax responsive element binding protein 5; Tax-responsive element-binding protein 5; TREB5; X box binding protein 1; X box binding protein 2; X-box-binding protein 1; XBP 1; XBP-1; XBP1; XBP1; XBP2
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Cancer; Epigenetics and Nuclear Signaling
Purification: Affinity purification
Concentration: 0.2 mg/mL
Dilution: IHC 1:50-1:200
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for XBP1 Polyclonal Antibody?

The catalog number for XBP1 Polyclonal Antibody is E-AB-14437.

What sizes are available for XBP1 Polyclonal Antibody?

XBP1 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does XBP1 Polyclonal Antibody come in?

XBP1 Polyclonal Antibody is available in 4 different pack sizes.

Is XBP1 Polyclonal Antibody in stock?

XBP1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures XBP1 Polyclonal Antibody?

XBP1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for XBP1 Polyclonal Antibody?

Estimated delivery time for XBP1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for XBP1 Polyclonal Antibody?

The safety data sheet for XBP1 Polyclonal Antibody is available here: https://789.bio/eb/Sq90OS.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.