ARHGEF7 Polyclonal Antibody

Specifications

Catalog number

E-AB-14609-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Abbreviation

ARHGEF7

UniProt

Q14155

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant protein of human ARHGEF7

Target

ARHG7; ARHG7; ARHGEF 7; Arhgef7; Beta pix; Beta-Pix; betaPix; betaPix-b; betaPix-c; Cool; COOL-1; COOL1; DKFZp686C12170; DKFZp761K1021; KIAA0142; KIAA0412; mKIAA0142; Nbla10314; P50; P50BP; p85; P85COOL1; P85SPR; PAK interacting exchange factor beta; PAK-interacting exchange factor beta; PAK3; Pak3bp; PIX; PIXB; Rho guanine nucleotide exchange factor (GEF) 7; Rho guanine nucleotide exchange factor (GEF) 7b; Rho guanine nucleotide exchange factor (GEF7) ; Rho guanine nucleotide exchange factor 7; SH3 domain containing proline rich protein

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Signal Transduction

Purification

Affinity purification

Concentration

0.2 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

90kDa

Isotype

IgG