GPM6A Polyclonal Antibody

Specifications

Catalog number

E-AB-14718-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Neuronal membrane glycoprotein M6-ais aproteinthat in humans is encoded by theGPM6Agene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs) ; enhances internalization and recycling of mu-type opioid receptor.

Abbreviation

GPM6A

UniProt

P51674

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant protein of human GPM6A

Target

GPM6A; GPM6A; M6a; Neuronal membrane glycoprotein M6-a; Neuronal membrane glycoprotein M6-a

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Neuroscience

Purification

Affinity purification

Concentration

0.4 mg/mL

Dilution

WB 1:1000-1:5000; IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

31kDa

Isotype

IgG