CBR1 Polyclonal Antibody

Specifications

Catalog number

E-AB-14736-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol.

Abbreviation

CBR1

UniProt

P16152

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant protein of human CBR1

Target

15 hydroxyprostaglandin dehydrogenase [NADP+];15-hydroxyprostaglandin dehydrogenase [NADP+]; Carbonyl reductase [NADPH] 1; Carbonyl Reductase 1; CBR 1; CBR1; CBR1; CRN; NADPH dependent carbonyl reductase 1; NADPH-dependent carbonyl reductase 1; Prostaglandin 9 ketoreductase; Prostaglandin 9-ketoreductase; Prostaglandin E (2) 9 reductase; Prostaglandin-E (2) 9-reductase; SDR21C1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Cell Biology; Metabolism; Signal Transduction

Purification

Affinity purification

Concentration

0.3 mg/mL

Dilution

WB 1:1000-1:5000; IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

30kDa

Isotype

IgG