CCDC106 Polyclonal Antibody

Specifications

Catalog number

E-AB-14831-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.

Abbreviation

CCDC106

UniProt

Q9BWC9

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Recombinant protein of human CCDC106

Target

CC106; Ccdc106; Coiled-coil domain-containing protein 106; HSU79303; Protein predicted by clone 23882; ZNF581

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer

Purification

Affinity purification

Concentration

0.5 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG