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Product details

DAB2 Polyclonal Antibody

Catalog number E-AB-14925-01

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Price for E-AB-14925-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-14925-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Abbreviation
DAB2
UniProt
P98082
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human DAB2
Target
DAB 2; Dab; mitogen-responsive phosphoprotein; homolog 2 (Drosophila) ; DAB2; Differentially expressed in ovarian cancer 2; Differentially expressed protein 2; Disabled (Drosophila) homolog 2 (mitogen responsive phosphoprotein) ; Disabled homolog 2; Disabled homolog 2 mitogen responsive phosphoprotein (Drosophila) ; Disabled homolog 2 mitogen responsive phosphoprotein; Disabled; Drosophila; homolog of;2; DOC 2; DOC2; FLJ26626; Mitogen responsive phosphoprotein
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Signal Transduction
Purification
Affinity purification
Concentration
0.6 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
82kDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for DAB2 Polyclonal Antibody?

The catalog number for DAB2 Polyclonal Antibody is E-AB-14925.

What sizes are available for DAB2 Polyclonal Antibody?

DAB2 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does DAB2 Polyclonal Antibody come in?

DAB2 Polyclonal Antibody is available in 4 different pack sizes.

Is DAB2 Polyclonal Antibody in stock?

DAB2 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures DAB2 Polyclonal Antibody?

DAB2 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for DAB2 Polyclonal Antibody?

Estimated delivery time for DAB2 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for DAB2 Polyclonal Antibody?

The safety data sheet for DAB2 Polyclonal Antibody is available here: https://789.bio/eb/T4arfP.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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