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Product details

GCK Polyclonal Antibody

Catalog number E-AB-15062-01

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Price for E-AB-15062-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-15062-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI) .
Abbreviation
GCK
UniProt
P35557
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human GCK
Target
ATP:D-hexose 6-phosphotransferase; FGQTL3; GCK; GK; GLK; Glucokinase; Hexokinase D pancreatic isozyme; Hexokinase type IV; Hexokinase-4; Hexokinase-D; HHF3; HK IV; HK4; HKIV; HXK4; HXKP; LGLK; MODY2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

Frequently Asked Questions

What is the catalog number for GCK Polyclonal Antibody?

The catalog number for GCK Polyclonal Antibody is E-AB-15062.

What sizes are available for GCK Polyclonal Antibody?

GCK Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does GCK Polyclonal Antibody come in?

GCK Polyclonal Antibody is available in 4 different pack sizes.

Is GCK Polyclonal Antibody in stock?

GCK Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GCK Polyclonal Antibody?

GCK Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for GCK Polyclonal Antibody?

Estimated delivery time for GCK Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for GCK Polyclonal Antibody?

The safety data sheet for GCK Polyclonal Antibody is available here: https://789.bio/eb/5ujXLC.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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